Аннотация
Список литературы
В Беларуси так же, как и во всём мире, ежегодное количество впервые выявленных злокачественных новообразований растёт. Активное вовлечение врачей-психотерапевтов, психиатров и психологов в процесс лечения и реабилитации пациентов является необходимой составной частью успешной противоопухолевой терапии, так как психическое состояние больных влияет как на само течение ракового заболевания, так и на качество их жизни. В данном литературном обзоре представлены абстракты статей из текстовой базы данных «Pubmed» по поисковому запросу «psycho-oncology», число которых по состоянию на декабрь 2019 года составило 5597, 2601 из которых были опубликованы за последние 5 лет (с 2014 года). Работа включает в себя последние данные, касающиеся вопросов молекулярного механизма и результата воздействия стресса на опухолевый процесс, спектра и распространённости ментальных расстройств у раковых больных, наиболее валидных инструментов их скрининга и диагностики, а также возможных методов медикаментозной и немедикаментозной терапии.
Ключевые слова:
психоонкология, рак, депрессия, дистресс, ПТСР, когнитивные дисфункции
Psycho-oncology at the current stage of development
Throughout the world, as well as in Belarus, the annual number of newly diagnosed malignant neoplasms is growing. The active involvement of psychotherapists, psychiatrists, and psychologists in the process of treating and rehabilitating patients is a necessary part of successful antitumor therapy, since the mental state of patients affects both the course of cancer and their quality of life. The following literature review presents abstracts of articles for the «psycho-oncology»search query from the Pubmed database. For December 2019, the number of those articles was 5597, 2601 of which had been published during the last 5 years (starting from 2014). The review includes the latest data on the molecular mechanism and the effects of stress on the tumour progression, the spectrum and prevalence of mental disorders in cancer patients, the most valid tools for their screening and diagnosis, as well as possible methods of pharmaceutical and non-pharmaceutical therapy.
Keywords
psycho-oncology, cancer, depression, distress, PTSD, cognitive dysfunctions
- 1. National Statistical Committee of the Republic of Belarus (2019) Statisticheskiiezhegodnik [Statistical Yearbook of the Republic of Belarus], Minsk, National Statistical Committee of the Republic of Belarus.
- 2. Lang-Rollin, I, Berberich G. Psycho-oncology. Dialogues in Clinical Neuroscience (electronic journal). – 2018. – Vol. 20, № 1. – P. 13–22. – Available at:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016045 (accessed 14 October 2019).
- 3. Holland, J. C. Psycho-oncology: Overview, obstacles and opportunities // Psychooncolog. – 2018. – Vol. 27, № 5. – P. 1364–1376. – doi: 10.1002/pon.4692.
- 4. Surman, M., Janik M. E. Stress and its molecular consequences in cancer progression. Postepy Higienyi Medycyny Doswiadczalnej (Online). – 2017. – Vol. 71, № 0. – P. 485–499. – doi: 10.5604/01.3001.0010.3830.
- 5. Shin, K. J. [et al.]. Molecular Mechanisms Underlying Psychological Stress and Cancer. Current Pharmaceutical Design. – 2016. – Vol. 22, № 16. – P. 2389–402. – doi: 10.2174/1381612822666160226144025.
- 6. Caruso, R., GiuliaNanni M., Riba M. B., Sabato S., Grassi L. Depressive Spectrum Disorders in Cancer: Diagnostic Issues and Intervention. A Critical Review. Current Psychiatry Reports. – 2017. – Vol. 19, № 6. – P. 33. – doi: 10.1007/s11920–017–0785–7.
- 7. Vodermaier, A., Linden W., & Siu C. Screening for Emotional Distress in Cancer Patients: A Systematic Review of Assessment Instruments. JNCI Journal of the National Cancer Institute. – 2009. – Vol. 101, № 21. – P. 1464–1488. – doi:10.1093/jnci/djp336.
- 8. Pascal, J. P. Management of Cancer-related Cognitive Dysfunction–Conceptualization Challenges and Implications for Clinical Research and Practice US Oncology. – 2010. – Vol. 6. – P. 9–12.
- 9. Kucherer, S., Ferguson R. J. Cognitive behavioral therapy for cancer related cognitive dysfunction. Current Opinion in Supportive and Palliative Care. – 2017. – Vol. 11, № 1. – P. 46–51.
- 10. J. Cara Pendergrass, Steven D. Targum, John E. Harrison. Cognitive Impairment Associated with Cancer.Innovations in Clinical Neuroscience(electronic journal). – 2018. – Vol. 15, № 1–2. – P. 36–44. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/ PMC5819720/#B7 (accessed 21 October 2019).
- 11. Pranjic, N., Bajraktarevic A., Ramic E. DISTRESS AND PTSD IN PATIENTS WITH CANCER: COHORT STUDY CASE. MATERIA SOCIO-MEDICA (electronic journal). – 2016. – Vol. 28, № 1. – P. 12–6. – Available at: https://www.ncbi.nlm.nih.gov/pubmed/27047260 (accessed 23 October 2019).
- 12. Carlson, L. E. [et al.]. The Role of Hypnosis in Cancer Care. Current Oncology Reports. – 2018. – Vol. 20, № 12. – P. 93. – doi: 10.1007/s11912-018-0739-1.
- 13. Chen, P. Y., Liu Y. M., Chen M. L. The Effect of Hypnosis on Anxiety in Patients With Cancer: A Meta-Analysis. Worldviews on Evidence Based Nursing. – 2017. – Vol. 14, № 3. – P. 223–236. – doi: 10.1111/wvn.12215.
- 14. NCCN (2020) Clinical Practice Guidelines in Oncology. Distress Management. Available at: https://www.nccn.org/professionals/physician_gls/pdf/distress.pdf (accessed 20 December 2019).
- 15. Nipp, R. D. [et al.]. Symptoms of posttraumatic stress disorder among hospitalized patients with cancer. Cancer. – 2018. – Vol. 124, № 16. – P. 3445–3453. – doi: 10.1002/cncr.31576.
- 16. Sleight, A. Coping with cancer-related cognitive dysfunction: a scoping review of the literature. Disability and Rehabilitation. – 2016. – Vol. 38, № 4. – P. 400–8. – doi: 10.3109/09638288.2015.1038364.