Resistant arterial hypertension has a high prevalence in patients with arterial hypertension. In the artical the risk factors of inadequate response to antihypertensive therapy have been introduced, the classification of resistant arterial hypertension have been given, genetic and immunological features of patients with resistant arterial hypertension have been described. Much attention waspaid to the arrangements for the treatment of resistant arterial hypertension: to the identification and correction of reversible risk factors, the improvement patient s adherence to therapy, to the diagnosis and the treatment of secondary forms of arterial hypertension, dose s canceling or reducing of concomitant drugs which exacerbate the resistance to the therapy. Medical and surgical approaches to treatment have been characterized.
- 1. Диагностика и лечение артериальной гипертензии / Рекомендации Российского медицинского общества по артериальной гипертонии и Всероссийского научного общества кардиологов) // Системные гипертензии. – 010. – № 3. – C. 5–27.
- 2. Козловская, И. Л. Лечение резистентной артериальной гипертонии: новые перспективы / И. Л Козловская, О. С. Булкина, Ю. А. Карпов // Кардиология. – 2012. – № 25. – C. 1238–1243.
- 3. Ливенцева, М. М. Виды рефрактерности к антигипeртензивной терапии и возможные пути ее преодоления / М. М. Ливенцева, Т. А. Нечесова // Медицинские новости. – 2013. – № 4. – С. 33–37.
- 4. Проект Регистр резистентной АГ (Регата) И. Е. Чазова [и др.] // Клиническая нефрология. – 2009. – № 2. – С. 52–54.
- 5. Резистентная артериальная гипертензия: диагностика, тактика и лечение / Научный доклад Профессионального комитета по профессиональному образованию при Совете по исследованиям в области повышенного артериального давления // Артериальная гипертензия СП. – 2008. – Т. 14, № 3. – С. 187–202.
- 6. Acute effects of passive smoking on blood pressure and heart rate in healthy females / M. Yarlioglues [et al.] // Blood Press Monit. – 2010. – Vol. 15. – P. 251–256.
- 7. Andersson, O. Management hypertension: clinical and hemodynamic studies with special reference to patients refractory to treatment/ O. Andersson// Acta Med. Scand. Suppl. – 1977. – Vol. 617. – P. 1–62.
- 8. Association between T786C NOS3 polymorphism and resistant hypertension: a prospective cohort study / I. Gruz-Gonzales [et al.] // BMC Cardiovasc. Disord. – 2009. – Vol. 9. – P. 35.
- 9. Benchefrits, S. Normokaliemichuperaldosteronism in patients with resistant hypertension / S. Benchefrits, J. Bethein, E. Podjarny // Isr. Med. ASSOS. J. – 2002. – Vol. 1. – P. 17–20.
- 10. Brown, M. A. Is resistant hypertension really resistant? / M. A Brown, M. J. Buddle, A. Martin // Am J Hypertens. – 2001. – Vol. 14, № 12. – P. 1263–1269.
- 11. Clinical and epidemiological characteristics of refractory hypertension in renal transplant patients / M. GagoFraile [et al.] // Transplant Proc. – 2009. – Vol. 41. – P. 2132–2133.
- 12. Clinical features of 8295 patients with resistant hypertension classified on the basis of ambulatory blood pressure monitoring / A. De la Sierra A. [et al.] // Hypertension. – 2011. – Vol. 57. – P. 171–174.
- 13. Common variants of the beta and gamma subunits of the epithelial sodium channel and their relation of the plasma renin and aldosterone levels in essential hypertension / T. Hannila-Handelberg [et al.] // BMC Medical Genetics. – 2005. – Vol. 6, № 4 doi: 10. 1186/1471–2350–6-4.
- 14. Cornelissen, V. A. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms and cardiovascular risk factors / V. A. Cornelissen, R. H. Fagard // Hypertension. – 2005. – Vol. 46. – P. 667–675.
- 15. CYP 3A5 genotype is associated with elevated blood pressure / M. F. Fromm [et al.] // Pharmocodenet. Genomics. – 2005. – Vol. 15, № 10. – P. 737–741.
- 16. Differential control of systolic and diastolic blood pressure: factors associated with lack of blood pressure control in the community / D. M. Lloyd-Jones [et al.] // Hypertension. – 2000. – Vol. 36. – P. 594–599.
- 17. Effecto falcoholabstinenceonbloodpressure: assesmentby 24-hourambulatory blood pressure monitoring / M. T. Aguilera [et al.] // Hypertension 1999. – Vol. 33, № 2. – P. 653–657.
- 18. Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial /E. Pimenta [et al.] // Hypertension. – 2009. – Vol. 54. – P. 475–481.
- 19. Evaluation and treatment of resistant hypertension / J. A. Slond [et al.] // Cardio Cogy Journal. – 2007. – Vol. 14, № 4. –P.329–339.
- 20. Fagard, R. H. Exercise therapy in hypertensive cardiovascular disease / R. H. Fagard // ProgCardiovasc Dis. – 2011. – Vol. 53. – P. 404–411.
- 21. Graudal, N. A. Effects of low-sodium diet vs. highsodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol and triglyceride (Cochrane Review). N. A. Graudal, T. Hubeck-Graudal, G. Jurgens // Am J. Hypertens. – 2012. – Vol. 25. – P. 1–15.
- 22. Guidelines for the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of European Society of Hypertension (ESH) and European Society of Cardiology (ESH)/G. Mancia [et al.] // J. Hypertens. – 2007. – Vol. 25. – P. 1105–1187.
- 23. Guidelinesfor the management of arterial hypertension: The Task Force for the Management of Arterial Hypertension of European Society of Hypertension (ESH) and European Society of Cardiology (ESH)/ G. Mancia [et al.] // J. Hypertens. – 2013. – Vol. 31. – P. 1281–1357.
- 24. Kaplan, N. Systolic Blood Pressure a determinant of Comorbidity / N. Kaplan // USA: Science Press. – 2004. – 52 p.
- 25. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials / H. O. Dickinson [et al.] // J. Hypertens. – 2006. – Vol. , № 24. – P. 215–233.
- 26. Perseill, S. D. Prevalence of resistant hypertension in United States, 2003 – 2008 / S. D. Perseill // Hypertension. – 2011. – Vol. 57. – P. 1076–1080.
- 27. Potential relevance of x1-adrenergic receptor autoantibodies in refractory hypertension /K. Wenzel [et al.] // PloS ONE. – 2008. – Vol. 3, № 11. – P. 3742.
- 28. Resistant hypertension: diagnosis, evaluation and treatment. A scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. / D. A. Calhoun [et al.] // Hypertension. – 2008. – Vol. 51. – P. 1403–1419.
- 29. Resistant hypertension revisited: a comparison of two university-based cohorts / J. P. Garg [et al.] // Am J. Hypertens. – 2005. – Vol. 18, № 5. – P. 619–626.
- 30. Risk of cardiovascular disease associated with refractory hypertension in renal transplant recipients / G. Fernandez-Fresnedo [et al.] // Transplant Proc. – 2010. – Vol. 42. – P. 2908–2909.
- 31. Success and predictors of blood pressure control in diverse North American settings: the Antihypertensive and Lipid-Lowering and Treatment to Prevent Heart Attask Trial (ALL HAT) / W. C. Cushman [et al.]// J Clin. Hypertens. – 2002. – Vol. 4. – P. 393–404.
- 32. Temporary reduction of blood pressure and sympathetic nerve activity in hypertensive patients after microvascular decompression / H. Frank H [et al.] // Stroke. – 2009. – Vol.40. – P. 47–51.
- 33. The impact of physical activity on mortality in patients with high blood pressure: a systematic review / A. Rossi [et al.] // J. Hypertens. – 2012. – Vol. 30. – P. 1277–1288.
- 34. Tobe, S. W. Resistant hypertension / S. W. Tobe, R. Lewamczuk // Can. J. Cardiol. – 2009. – Vol. 25, № 5. – P. 315–317.
- 35. Twenty four ambulatory blood pressure monitoring pattern of resistant hypertension / E. S Muxfeldt[et al.] // Blood Press Monit. – 2003. – Vol. 8, № 5. – P. 181–185.
- 36. Vidt, D. G. Contributing factors resistant hypertension: Truly refractory discase in rarely found in a properly conducted workup / D. G. Vidt // Postgrad. Med. – 2000, May I. – Vol. 107. – P. 5.
- 37. Viera, A. J. Evaluation and management of the patients with difficult-to-control or resistant hypertension / A. J. Viera, A. L. Hinderliter// American Family.