С. Э. Глазкова, И. А. Карпов, Д. Е. Данилов, М. Мунтеану
ИООО «Синэво», Минск, Беларусь, УО «Белорусский государственный медицинский университет», Госпиталь Питье Сальпетриер, Париж, Франция
В работе изложены современные подходы к использованию неинвазивных методов диагностики в инфекционной гепатологии, приводится подробный анализ эффективности их использования при исследовании печени, и описаны их преимущества перед пункционной биопсией. Рассматриваются возможные отклонения и недостатки в использовании различных методов, обсуждается тактика комплексного использования неинвазивных методик: определение стадий фиброза печени на основе сывороточных маркеров (панель FibroTest) и транзиентной эластографии. В данной работе впервые представлены результаты исследований с использованием неинвазивного метода диагностики патологий печени – применения панели сывороточных биомаркеров FibroTest. Были определены и описаны наличие и стадии фиброзных изменений в печени у пациентов различных групп риска с печеночной патологией, направленных на исследование лечащими врачами с диагностической целью.
ключевые слова: неинвазивные методы исследования, сывороточные маркеры, эластография, FibroTest, патология печени, фиброз
Non-invasive diagnostic methods of infectious pathology
S. Е. Glazkova, I. А. Karpov, D. Е. Danilau, M. Munteanu
The paper describes the modern approaches to the use of non-invasive diagnostic methods in infectious Hepatology, provides a detailed analysis of the effectiveness of their use in the study of the liver, and describes their advantages to the needle biopsy. The possible deviations and defects in the use of different methods are shown, as well as the tactics of complex use of non-invasive techniques: identification of liver fibrosis stage based on serum markers (FibroTest panel) and transient elastography. In this study, the results of non-invasive method – the serum biomarkers panel FibroTest – for diagnosing pathologies of the liver is shown for the first time. They have been identified and described the presence and stage of liver fibrosis in patients with various risk of hepatic pathology, sent for the research by their treating physicians for diagnostic purposes.
keywords: non-invasive diagnostic methods, serum markers, elastography, FibroTest, liver pathology, fibrosis
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