Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. In this pathology, the morphofunctional characteristics of the endometrium have features that cause violations of the realization of reproductive function and unfavorable outcomes of gestation, as well as the risk of developing endometrial cancer. According to the study, the normal characteristic of the endometrium was found in 22 (44.9 %). In the structure of endometrial pathology in patients with PCOS, endometrial polyps accounted for a significant proportion – 16 (32.6 %) patients, chronic endometritis – 30 (61.2 %), simple endometrial hyperplasia – 7 (14.2 %). Functional pathology was also noted: proliferative endometrium with pathology (anovulatory endometrium) was found in 9 patients (18.3 %), endometrial hypoplasia – in 7 (14.2 %). PCOS has a high incidence of endometrial pathology, which necessitates the development of clinical approaches for the diagnosis and correction of the pathology.
- 1. Ковалева, Ю. В. Лечение ановуляторного бесплодия у больных с синдромом поликистозных яичников / Ю. В. Ковалева // Проблемы репродукции. Материалы IV международного конгресса по репродуктивной медицине. – 2011. – 319 с.
- 2. Кондриков, Н. И. Патология матки. Руководство для врачей / Н. И. Кондриков, И. В. Баринова. – 2е изд. – М.: Практическая медицина, 2019. – 352 с.
- 3. Кулаков, В. И. Вспомогательные репродуктивные технологии – настоящее и будущее / В. И. Кулаков // Лечение женского и мужского бесплодия. – М.: Медицинское Информационное Агентство, 2005. – С. 11–12.
- 4. Оразов, М. Р. Хронический эндометрит: патогенез, диагностика, лечение и его связь с бесплодием / М. Р. Оразов, Л. М. Михалева, П. А. Семенов // Клиническая и экспериментальная морфология. – М., 2020. – № 2. – С. 16–25.
- 5. Chittenden, B. G. Policystic Ovary Syndrome and Risk of Gynaecological Cancer: A Systematic Review / B. Chittenden, G. Fullerton, A. Maheshwari, S. Bhattacharya // Reprod Biomed. – 2009. – № 3. – Р. 398–405.
- 6. Cicinelli, E. Chronic Endometritis in Patients with Unexplained Infertility: Prevalence and Effects of Antibiotic Treatment on Spontaneous Contraception / E. Cicinelli, M. Matteo, G. Trojano, P. Mitola, R. Tinelli, A. Vitagliano, F. Crupano, A. Lepera, G. Miragliotta, L. Restall // Am J Reprod Immunol. – 2018. – № 1.
- 7. Haoula, Z. Evaluaning the Association between Endometrial Cancer and Policystic Ovary Syndrome / Z. Haoula, M. Salmon, W. Atiomo // Hum Reprod. – 2012. – № 5. – Р. 1327–31.
- 8. Kimura, F. Rewiew: Chronic Endometritis and Its Effect on Reprodaction / F. Kimura, A. Takebayashi, M. Inshida, A. Nacamura, J. Katazowa, A. Morimune, K. Hirata, A. Takahashi, S. Tsuji // J Obstet Gynecol Res. – 2019. – № 5. – Р. 951–960.
- 9. Kurman, R. World Health Organisation Classification of tumors of female reproductive organs / R. Kurman, M. Carcangiu, C. Herrington, R. Young // 4th ed. – Lyon, France: IARC Press, 2014.