Group B Streptococcus is one of the most frequent causative agent of neuroinfections in infants.Aim: to reveal predictors of unfavorable outcome of neuroinfection by clinical and laboratory features analysis. Subject. 58 infants with neuroinfection, caused by Group B Streptococcus. All patients were divided into 2 groups: with good outcome and with unfavorable outcome of neuroinfection.Result. Hypotension, microvascular perfusion disorder, focal neurological signs, indications for artificial lung ventilation, alteration of consciousness, intestinal distention and seizures are clinical predictors of unfavorable outcome of neuroinfection caused by Group B Streptococcus. Leucopenia and neutropenia are laboratory predictors of unfavorable outcome of neuroinfection.
- 1. Мартынов, В. А. Осложнения бактериальных менингитов / В. А. Мартынов, Л. Г. Жданович, Е. А. Карасева [и др.] // Инфекционные болезни: новости, мнения, обучение. – 2018. – Т. 7, № 1. – С. 54–59.
- 2. Милованова, О. А. Неврологические последствия и исходы бактериальных менингитов у детей / О. А. Милованова, Л. Н. Мазанкова, Д. А. Моисеенкова, И. А. Солдатова // Журнал неврологии и психиатрии им. С. С. Корсакова. Спецвыпуски. – 2016. – Т. 4, № 116. – С. 4–11.
- 3. van de Beek, D. ESCMID guideline: diagnosis and treatment of acute bacterial meningitis / D. van de Beek [et al.] // Clinical Microbiology and Infection. – 2016. – P. 1–26.
- 4. Brouwer, M. C. Epidemiology, diagnosis and antimicrobial treatment of acute bacterial meningitis / M. C. Brouwer, A. R. Tunkel, D. van de Beek // Clinical microbiology reviews. – 2010. – № 23 (3). –P. 467–492.
- 5. Coates, T. D. Overview of neutropenia in children and adolescents [Electronic resource] / T. D. Coates // UpTo-Date. – Mode of access: htts://www.uptodate.com/contents/overview-of-neutropenia-in-children-and-adolescents. – Date of access: 19.07.2019.
- 6. Heath, P. T. Neonatal meningitis / P. T. Heath, N. K. Nik Yusoff, C. J. Baker // Arch Dis Child Fetal Neonatal Ed. – 2003. – № 88. – P. 173–178.