Cancer is one of the leading causes of death worldwide. A change in the mutual regulation between the structural elements of the neoplasm leads to the progression of the tumor process. The aim of this study was to determine the parenchymal-stromal ratio in Erlich’s transplantable solid carcinoma, the stromal component of which is represented by a dense network of blood vessels. In the later stages of removal of Erlich’s transplantable carcinoma, a significant decrease in the parenchymal-stromal ratio is noted. The area of the stromal component significantly differed at different periods of growth of Erlich transplanted carcinoma (p = 0.039), which was accompanied by a drop in the parenchymal-stromal ratio (p = 0.032). The study of the parenchymal-stromal ratio can be used to predict an adverse outcome and target therapeutic effects.
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