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«Кишечник микробиота мозг» при нейродегенеративных заболевания

А. Т. Быков, Т. Н. Маляренко ГБУ ВПО «Кубанский государственный медицинский университет Минздрава России»
2017 №4 | Лекции
Аннотация
Список литературы
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В представляемой обзорной статье основное внимание сфокусировано на деменции и болезни Альцгеймера (БА) в связи с интенсивным распространением во всём мире этих социально значимых нейродегенеративных заболеваний, что расценивается ВОЗ как быстро нарастающая эпидемия. Обсуждается концепция и механизмы взаимосвязи кишечной микробиоты с мозгом по двусторонней оси «кишечник-микробиота-мозг» в патогенезе деменции и БА.
Ключевые слова:
болезнь Альцгеймера, кишечная микробиота, профилактика, пробиотики
Gut microbiota brain axis and neurodegenerative diseases

In the focus of this review are dementia and Alzheimer's disease (AD) in connection with the intensive spread of these socially significant neurodegenerative diseases throughout the world, what is regarded by WHO as a rapidly growing epidemic. The concept and mechanisms of the rela-tionship of the intestinal microbiota with the brain on the bilateral axis "gut-microbiota-brain" in the pathogenesis of dementia and AD are discussed.

Keywords
Alzheimer's disease, intestinal microbiota, prevention, probiotics
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