The article presents a retrospective analysis of medical histories of patients with miscarriage of early terms, as well as the results of morphological studies of endometrial biopsy specimens of the same patients. The problem of spontaneous premature termination of pregnancy has not only medical, but also socio-economic and psychological significance. Among the most urgent problems of obstetrics, miscarriage, occupies one of the first places, since it negatively affects the level of fertility. The significance of the diagnosis of early miscarriage by a histological method is shown - the detection and systematization of morphological changes in biopsy specimens. It was revealed that, in the morphological study of endometrial biopsy, the most frequent etiopathological factors of spontaneous abortions are: a gravity corpus luteum (57%), infectious pathology (32%), as well as violation of differentiation of chorionic villi (6%).
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