The article is devoted to the features of the physical development evaluation in children with Down syndrome (DS). Children with DS have a reduced growth rate, the cause of which has not yet been clearly identified. Therefore, the assessment of the growth rate in children with trisomy of 21 st pair of chromosomes with graphs designed for ordinary children is not informative. To assess the physical development of these children it is necessary to use the table designed for children with DS based on racial and ethnic characteristics of the specific region. This kind of percentile charts have been already designed in the United States, Portugal, Sweden, the UK and other countries. The article presents a comparative data of the physical development evaluation in children with DS by the standard percentile charts and special charts, developed for children with DS (United States). It is shown that, when assessing the growth with special charts, most of the children had medium and high growth levels, while in the measurement with standard growth charts the majority of children assessed the result of a low or lower than average; according to special charts most of the children had weight indicators as average and above average, and low and below the average according to the standard charts.
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