The characteristics of etiologic agents of pyelonephritises are ability to form biofilm, the structure and physiological nature of which provide decreased susceptibility to antibiotics, antiseptics, and to immune system. The article presents the estimation of ability to form of biofilms of etiologic agents of acute and chronic pyelonephritises. The bacterial strains E. coli, P. aeruginosa, K. pneumoniae, S. aureus, isolated from patients with chronic pyelonephritis by ability to form biofilms have surpassed than the strains isolated from patients with acute pyelonephritis. The maximum film-forming ability P. aeruginosa isolates are possessed. Intensity of formation of biofilms was above by strains of microorganisms isolated from patients with pyelonephritises with accompaning of urolithiasis.
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