А.П. Музыченко, Т.А. Сикорская, М.В. Качук
УО «Белорусский государственный медицинский университет»
Псориаз  хроническое, воспалительное, мультифакторное заболевание с преимущественным поражением кожи, которым страдает приблизительно 2-3% населения. Лечение должно быть адаптировано для каждого конкретного пациента. Мы детально обсудим эффективность и безопасность использования синтетического ретиноида ацитретина при псориазе. В настоящее время его применение одобрено FDA для лечения тяжелых форм псориаза у взрослых, а также он может применяться в качестве терапии второй линии псориаза, резистентного к использованию топической терапии.
ключевые слова: псориаз, ароматические ретиноиды, ацитретин, PASI
Modern therapeutic considerations for severe psoriasis
A.P. Muzychenkа, T.A. Sikorskayа, M.V. Kachuk
Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2-3% of the population.Treatment should be tailored to meet individual patients’ needs. We will discuss in detail the efficacy and safety for the use a synthetic retinoid acitretin in psoriasis. It is currently approved by the US Food and Drug Administration for the treatment of severe psoriasis in adults and has been established as a second-line therapy for the treatment of psoriasis resistant to the use of topical therapy.
keywords: psoriasis, aromatic retinoid, acitretin, PASI
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