Аннотация
Список литературы
Цель работы – изучить влияние артериальной гипертензии и гипергликемии при сахарном диабете на морфологические параметры сосудов парамакулярной области глазного дна для выявления различий в состоянии микроциркуляторных сосудов сетчатки глаза и кардиоваскулярных рисков.
Ключевые слова:
сосуды глазного дна, парамакулярная область, сахарный диабет, диабетическая ретинопатия, гипергликемия, артериальная гипертензия, гипертоническая ретинопатия
Differences in morphological parameters of the vessels of the paramacular retina area in patients with arterial hypertension and in patients with diabetes mellitus
Objective –to study the effect of arterial hypertension and hyperglycemia in diabetes mellitus on the morphological parameters of the paramacular area vessels of the eye fundus to identify differences in the state of the retina vessels and cardiovascular risks.
Keywords
retinal vessels, paramacular area, diabetes mellitus, diabetic retinopathy, hyperglycemia, arterial hypertension, hypertensive retinopathy
- 1. Смирнова, О. М. Диабетическая ретинопатия. Результаты международных многоцентровых исследований / О. М. Смирнова // Сахарный диабет. – 2010. – T. 13, № 1. – С. 82–87.
- 2. End-organ dysfunction and cardiovascular out comes: the role of the microcirculation / C. J. Lockhart [et al.] // Clinical. Science. – 2009. – Vol. 116 (3). – P. 175–190.
- 3. Hypertensive retinopathy revisited: some answers, more questions / A. Grosso [et al.] // British Journal of Ophthalmology. – 2005. – Vol. 89. – P. 1646–1654.
- 4. Kannel, W. B. Blood pressure as a cardiovascular risk factor: prevention and treatment / W. B. Kannel // JAMA, J. Am. Med. Assoc. – 1996. – Vol. 275. – P. 1571–1576.
- 5. Effects of age and blood pressure on the retinal arterial wall, analyzed using adaptive optics scanning laser ophthalmoscopy / A. Shigeta [et al.] // Scientific Reports. – 2015. – Vol. 5. – P. 1–10.
- 6. Imaging retina to study dementia and stroke / C. Y. Cheung [et al.] // Progress in Retinal and Eye Research. – 2017. – Vol. 57. – P. 89–107.
- 7. Lockhart, C. J. Measuring endothelial function / C. J. Lockhart, G. E. McVeigh,J. N. Cohn// Curr. Diabetes Rep. – 2006. – Vol. 6. – P. 267–273.
- 8. Impaired microvascular dilatation and capillary rarefaction in young adults with a predisposition to high blood pressure /J. P. Noon [et al.] // J. Clin. Invest. – 1997. – Vol. 99. – P. 1873–1879.
- 9. Retinal vessel diameters and risk of hypertension: the Rotterdam Study / M. K.Ikram [et al.] // Hypertension. – 2006. – Vol. 47. – P. 189–194.
- 10. Early narrowed afferent arteriole is a contributor to the development of hypertension / H.Norrelund [et al.] // Hypertension. – 1994. – Vol. 24. – P. 301–308.
- 11. Are retinal arteriolar or venular diameters associated with markers for cardiovascular disorders? The Rotterdam Study / M. K. Ikram [et al.] // Invest. Ophthalmol. Visual Sci. – 2004. – Vol. 45. – P. 2129–2134.
- 12. Tooke, J. E. Microvascular function in human diabetes: a physiological perspective / J. E. Tooke // Diabetes. – 1995. – Vol. 44. – P. 721–726.
- 13. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes / A. E. Caballero [et al.] // Diabetes. – 1999. – Vol. 48. – P. 1856–1862.
- 14. Retinal arteriolar narrowing and risk of diabetes mellitus in middle-aged persons / T. Y. Wong [etal.] // JAMA, J. Am. Med. Assoc. – 2002. – Vol. 287. – P. 2528–2533.
- 15. Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study / M. K. Ikram [et al.] // Diabetes. – 2006. – Vol. 55. – P. 506–510.
- 16. Wong, T. Y. Hypertensive retinopathy / T. Y. Wong, P. Mitchell // N. Engl. J. Med. – 2004. – Vol. 351. – P. 2310–2317.
- 17. Diabetic retinopathy and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study / N.Cheung [et al.] // DiabetesCare. – 2007. – Vol. 30. – P. 1742–1746.
- 18. Retinal vascular image analysis as potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures / N. Patton [et al.] // Journal of Anatomy. – 2005. – Vol. 206. – P. 319–348.
- 19. Thompson, Сh. S Living beyond our physiological means: small vessel disease of the brainis an expression of a systemic failure in arteriolar function: a unifying hypothesis / Сh. S. Thompson, A. M. Hakim // Stroke. – 2009. – Vol. 40. – P. 322–330.
- 20. Fractal analysis of retinal vessels suggests that a distinct vasculopathy causes lacunar stroke / F. N. Doubal [et al.] // Neurology. – 2010. – Vol. 74 (14). – P. 1102–1107.
- 21. Retinal microvascular abnormalities and cognitive dysfunction: a systematic review / J. Ding [etal.] // British Journal of Ophthalmology. – 2008. – Vol. 92. – P. 1017–1025.
- 22. Meta-analysis: retinal vessel caliber and risk for coronary heart disease / K. McGeechan [etal.] // Annals of Internal Medicine. – 2009. – Vol. 151. – P. 404–413.
- 23. Blum, M. The eye, the kidney and microcirculation /M. Blum, A. Saemann, G. Wolf // Nephrol Dial Transplant. – 2011. – Vol. 26. – P. 4–6.
- 24. D’Souza, Y. B. The eye–a window on the kidney /Y. B. D’Souza, C. D. Short // Nephrol Dial Transplant. – 2009. – Vol. 24. – P. 3582–3584.
- 25. Ohno, T. Diabetic retinopathy and coronary artery disease from the cardiac surgeon’s perspective / T. Ohno, S. Takamoto, N. Motomura // Ann. Thorac. Surg. – 2008. – Vol. 85. – P. 681–689.
- 26. Состояние сосудов сетчатки, световой и контрастно-цветовой чувствительности у пациентов с артериальной гипертензией / А. И. Кубарко [и др.] // Офтальмология. Восточная Европа. – 2014. – № 4 (23). – С. 223–231.
- 27. Микроциркуляторные изменения в сетчатке при диабетической ретинопатии / Г. В. Рева [и др.] // Успехи современного естествознания. – 2004. – № 8 – С. 65–66.
- 28. Vascular endothelial growth factor-B in physiology and disease / M. Bry [et al.] // Physiol Rev. – 2014. – Vol. 94. – P. 779–794.
- 29. Retinal Vascular Caliber as a Biomarker for Diabetes Microvascular Complications / M. K. Ikram [et al.] // Diabetes Care. – 2013. –Vol. 36. – P. 750–759.
- 30. Wong, T. Y. Is retinal photography useful in the measurement of stroke risk? / T. Y. Wong // Lancet Neurol. – 2004. – Vol. 3. – P. 179–183.
- 31. Fractal analysis of retinal vessels suggests that a distinct vasculopathy causes lacunar stroke / F. N. Doubal [et al.] // Neurology. – 2010. – Vol. 74 (14). – P. 1102–1107.
- 32. Biomarkers of diabetic nephropathy, the present and the future / B. Jim [et al.] // Diabetes Rev. – 2012. – Vol. 8. – P. 317–328.
- 33. Retinal vessel diameters and reactivity in diabetes mellitus and/or cardiovascular disease / R. Heitmar [et al.] // Cardiovasc Diabetol. – 2017. – Vol. 16. –P. 56–65.
- 34. Childhood vascular risk factors and retinal vessel caliber / N. Cheung [et al.] // Asia Pac. J. Ophthalmol. – 2012. – Vol. 1. – P. 193–197.
- 35. Pugh, C. W. Regulation of angiogenesis by hypoxia: role of the HIF system / C. W. Pugh, P. J. Ratcliffe // Nat. Med. – 2003. – Vol. 9 – P. 677–684ю
- 36. Состояние сосудов сетчатки, световой чувствительности зрительной системы и их связь со структурными изменениями в головном мозге у пациентов с артериальной гипертензией / Кубарко А.И. [и др.] // Неотложная кардиология и кардиоваскулярные риски. – 2017. – T. 1, № 1. – C. 89–98.